EXCHANGE OF MATERIALS ACROSS PLASMA MEMBRANE

The plasma membrane is a thin layer of fat and protein covering the surface of every cell; it acts as a selective barrier that regulates the passage of substances in and out of cells. These substances are involved in the metabolic processes in the cell, some of them crosses the barrier without difficulties while others passes slowly with much difficulties, yet others are entirely stopped from entering.


PROCESSES BY WHICH MATERIALS MAYBE EXCHANGED ACROSS A MEMBRANE   
 
   DIFFUSION: - This is the movement of molecules from an area of higher concentration to that of a lower concentration through concentration gradients with the aim of balancing concentration on both sides of a membrane.

A Concentration Gradient is a region of high concentration of solute on one side of a membrane and a region of low concentration of solute on the other side.

During diffusion, molecules spread into an available space; this is due to thermal energy present in molecules at temperature above absolute zero. The rate of diffusion of substances is affected by membrane permeability since membrane selectively permeable.

   2. DIFFUSION CHANNEL: - Water and dissolved ions being charged cannot diffuse through the phospholipids component of the plasma membrane; rather they pass through specialized pore of channels created by transmembrane protein. 

Ion channel allows specific ions of certain size and charge to diffuse at all time or they maybe gated channels that need signal to open.  Gated channels may open or close when a signaling molecule binds to specific binding site on transmembrane protein. 

    3. CARRIER MEDIATED TRANSPORT: - Nutrients such as   sugar, waste products and amino acid are transported across a cell by special membrane protein known as transporters or carriers.   There are three  types of mediated transport,

a – Active transport:- Energy is used to move molecules in direction opposite to a concentration gradient. The energy used is called Proton Motive Force and its gotten from Adenosine Triphosphate(ATP) or co enzyme.

b – Passive diffusion: - This is the movement of substance from region of higher to lower concentration at a rate proportional to the concentration difference of the membrane without the use f energy or special molecule. Passive transport is a spontaneous process that takes place because of entropy of a system. 

b(1) Facilitated diffusion: - is a kind of passive where proteins    (carrier molecules) help substances to diffuse across a membrane that it ordinarily cannot pass through.   This type of transport process increases the speed of molecules by making it move rapidly, the protein spurn the membrane and selectively increase the permeability of the membrane for specific molecules. Sodium ion, chlorine and glucose cannot cross the phospholipids bilayer guarding a cell, but with the help of carrier proteins, and ion channels these substances are moved across the cell.


OSMOSIS: - Water molecule can move across any membrane without resistance if there is a high concentration on one side and a low concentration on the other side, water molecule will diffuse across the membrane from a solution of lower concentration (hypotonic) to that of higher osmotic concentration (hypertonic) through a semi permeable membrane.

Osmosis is a selective diffusion driven by internal energy of solvent molecule.

 When a solution of sugar is separated from pure water by a membrane permeable to water but not sugar, (semi permeable membrane), water crosses into the sugar solution, the movement of water is what illustrates osmosis. If external pressure is applied to the sugar solution, the movement of water will be opposed. The pressure needed to prevent the flow of water is called osmotic pressure, and the more concentrated the solution the greater it is.

The amount of osmotic pressure produced by solution in standard condition depends on the number of dissolved solute particles, molecules ions relative to their sizes in a given amount of water.

Osmosis plays an important role in controlling the distribution of water in living organism.

b(3) –Filtration – This uses hydrostatic pressure to transport solute, solvent molecules and ions across a membrane.

Other ways materials can be move across a cell are mainly used to carry solid materials.

      1. ENOCYTOSIS :- the term describes three related processes,
      a – Phagocytosis :-   This means cell ‘eating’, in this process, an area of the plasma membrane coated externally with actin and actin binding proteins forms a pocket that engulfs the solid material eg bacteria, the membrane enclosed vesicle or phagosome then detaches from the cell surface and move into the cytoplasm where it fuses with lysosome and it contents are digested.
 
  b – Pinocytosis :- This is similar to phagocytosis except that it involves engulfing liquid, very small invaginations are formed on the surface if the cell membrane, these then close  to form fluid filled vesicles.

  c – Exocytosis :-  The membrane of vesicle can fuse with the plasma membrane  which then rupture and discharge its contents. Exocytosis is the exchange of material across Plasma membrane where by secretory granules or droplets are released from a cell.

CITATIONS
Integrated principle of Zoology  14th edition by Hickman, Robberts, Keenn, Larson, Panson and Elsenchour.
Wikipedia the free encyclopedia.
Cell biology, by Stephen Ojo.
Dictionary of biology, By Uvarov, Chapman and  Isaacs.
Stedman’s medical dictionary for health professions,by Dirckk, university of Dayton Student Health Centre Dayton, Ohio.





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